Antipsychotic Metabolic Effects: Weight Gain, Diabetes Mellitus, and Lipid Abnormalities
نویسندگان
چکیده
منابع مشابه
Clozapine: diabetes mellitus, weight gain, and lipid abnormalities.
Clozapine remains the most effective agent for treatment-resistant patients with schizophrenia. Recently, treatment with clozapine has been linked to a number of metabolic disturbances, including weight gain, diabetes mellitus, and serum lipid abnormalities. Despite the potential risks of medical morbidities, clozapine continues to have a major role in the care of treatment-resistant patients w...
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The seriously mentally ill have significantly more cardiovascular risk factors, receive less appropriate medical care, and die on average 15 to 30 years earlier than the general population, mostly because of cardiovascular disorders (1). Reasons for this physical health disparity are complex and include unhealthy lifestyle behaviors, illness-related effects (including poverty, negative symptoms...
متن کاملAntipsychotic Medication and Diabetes Mellitus
Sir: Spoelstra and colleagues assert that antipsychotic drugs may worsen metabolic control in type 2 diabetes mellitus and speculate from their pharmacoepidemiologic study that this worsening is probably due to β-cell toxicity. While there is general agreement that exposure to antipsychotic medications (and second-generation agents in particular) may be associated with an increased risk of diab...
متن کاملAntipsychotic medication and diabetes mellitus.
Sir: Spoelstra and colleagues assert that antipsychotic drugs may worsen metabolic control in type 2 diabetes mellitus and speculate from their pharmacoepidemiologic study that this worsening is probably due to β-cell toxicity. While there is general agreement that exposure to antipsychotic medications (and second-generation agents in particular) may be associated with an increased risk of diab...
متن کاملWeight gain and gestational diabetes mellitus is a sensitive issue.
Normal pregnancy is associated with reduced insulin sensitivity, compensatory increase in insulin secretion, and small changes in circulating nutrients. Gestational diabetes mellitus (GDM) occurs when insulin secretion is insufficient to compensate for the insulin resistance of pregnancy. During late pregnancy, women with GDM tend to be more insulin resistant than obesity-matched women with nor...
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ژورنال
عنوان ژورنال: The Canadian Journal of Psychiatry
سال: 2001
ISSN: 0706-7437,1497-0015
DOI: 10.1177/070674370104600308